Bioactive Peptides: Advancing Functional Foods innovation
Bioactive peptides are fragments of protein that exhibit diverse functionalities upon release from their original structure, potentially yielding significant pharmaceutical effects. They can manifest as antihypertensive, antioxidant, antimicrobial, antidiabetic, or immunomodulatory agents depending on the amino acid composition, size, sequences, and physicochemical properties.
The primary goal of our research group is to explore various protein sources such as yeast cells, seaweed, and marine protein for specific peptide sequences with significant health benefits, employing an enzymatic hydrolysis approach. Our second goal is to discover the structure-function relationship of bioactive peptide and their action mechanism through in vitro, in silico and cell culture models. In addition, we aim to evaluate peptides for bioavailability by simulating gastrointestinal digestion system and using epithelial cell culture model and to employ a suitable delivery system for improving peptide`s bioavailability. Ultimately, our overarching aim is to develop novel functional foods using the identified peptide sequences for improving the society health.
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We provide knowledge and expertise on topics like:
- Purification of antioxidant, antihypertensive, and antidiabetic peptides from different protein sources
- Evaluating peptides for structure-function relationship, activity mechanism, and bioavailability
- Employing suitable drug delivery system to enhance peptide’s bioavailability